折臂式随车起重机转台的拓扑优化设计

为了使折臂式随车起重机转台在最大应力不超过材料许用应力的前提下实现轻量化设计的目的,通过ADAMS软件仿真确定其极限工况,对转台进行静力学分析及拓扑优化。通过拓扑优化得到了理想的材料分布。基于优化结果调整转台结构,并对改进后的转台进行静力学分析。结果表明,优化后的转台能够满足实际的使用需求。同时,转台质量降低了12%,证明了优化设计的有效性和可行性,并为折臂式随车起重机的相关设计提供了一定的借鉴。     

木姜子挥发油与β-环糊精包合工艺的优化

以新鲜木姜子果实为原料,通过水蒸气蒸馏法提取木姜子挥发油;利用饱和水溶液法进行β-环糊精与挥发油包合物的制备,包合工艺的优化采用星点设计-响应面法进行。结果表明,木姜子挥发油与β-环糊精最佳包合工艺为:投料比1:5.77(mL:g),包合时间4.09 h,包合温度51.5℃。利用UV、IR、TG和SEM对包合物表征,表征结果显示,木姜子挥发油与β-环糊精已经形成包合物。研究结果可为木姜子挥发油的进一步实际利用提供可靠参考。     

PWR堆芯燃料组件非线性梁模型研究

为描述燃料组件的非线性特性，采用有限元方法建立燃料组件横向梁模型，并引入迟滞模型，用于模拟燃料组件横向变形时的非线性效应。计算结果表明:该非线性梁模型能够更准确地获得组件的弯曲变形和受力，有助于开展燃料组件事故分析。      

Relationship Between Shipping Accessibility and Maritime Transport Demand: the Case of Mainland China

Networks and Spatial Economics - The relationship between shipping accessibility and maritime transport demand is studied based on the relationship between production and consumption and stochastic...     

Long-term sustained-released in situ gels of a water-insoluble drug amphotericin B for mycotic arthritis intra-articular administration: preparation,in vitro and in vivo evaluation

Amphotericin B (AMB) was often used in intra-articular injection administration for fungal arthritis, because it could often bring a satisfactory therapeutic efficacy and a minimum systemic toxic side effect. However, because of the multiple operations and the frequent injections, the compliance of the patients was bad. Therefore, to develop a long-term sustained-released preparation of AMB for mycotic arthritis intra-articular administration is of great significance. The purpose of present study was to develop a long-term sustained-released in situ gel of a water-insoluble drug AMB for mycotic arthritis intra-articular administration. Based on the evaluations of the in vitro properties of the formulations, the formulation containing 10% (w/w) ethanol, 15% (w/w) PG, 0.75% (w/w) HA, 5% (w/w) purified soybean oil, 0.03% (w/w) α-tocopherol, 15% (w/w) water and 55% (w/w) glyceryl monooleate was selected as a suitable intra-articular injectable in situ gel drug delivery system for water-insoluble drug AMB. Furthermore, the results of the in vivo study on rabbits showed that the selected formulation was a safe and effective long-term sustained-released intra-articular injectable AMB preparation. Therefore, the presented in situ AMB gel could reduce the frequency of the administration in the AMB treatment of fungal arthritis, and then would get a good patient compliance.     

Quality enhancement of the abundant under‐valued crustacean,lobster krill (Munida spp.), during its chilled storage

Lobster krill (Munida genus) represents an under‐valued crustacean frequently caught on European fishing banks. In this work, its sensory, microbiological and biochemical qualities were evaluated during chilled storage. Additionally, the effects of a prestorage antimelanosic treatment consisting of soaking in sodium metabisulphite (SMB) solutions at two different concentrations (0.25% and 0.75%) were also studied. SMB prestorage treatment provided lobster specimens that still exhibited acceptable sensory quality after 10 days of storage, while control specimens were unacceptable at that time. SMB treatment also resulted in a significant (P < 0.05) inhibition of microbial growth, mainly of Enterobacteriaceae, psychrotrophes and proteolytic bacteria. Low lipid oxidation levels were observed for all batches; however, a significantly higher (P < 0.05) retention of polyunsaturated fatty acids was found in SMB‐treated lobster, especially in the 0.75% SMB batch. The results presented here open the way to the potential commercialisation of currently under‐utilised lobster krill as a chilled product.